T cells count and then decide

T cells count and then decide

JCB • VOLUME 180 • NUMBER 4 • 2008 650 T cells count and then decide T cells tabulate the density of antigens in their surroundings before deciding whether to activate, say Sarah Henrickson, Ulrich von Andrian (Harvard Medical School, Boston, MA), and colleagues. In a prior study, von Andrian says, his group had noticed T cells within lymph nodes fl it “like bumblebees” from one antigen-present...

Track, then Decide: Category-Agnostic Vision-based Multi-Object Tracking

The most common paradigm for vision-based multi-object tracking is tracking-by-detection, due to the availability of reliable detectors for several important object categories such as cars and pedestrians. However, future mobile systems will need a capability to cope with rich human-made environments, in which obtaining detectors for every possible object category would be infeasible. In this p...

Frequency of Efficient Circulating Follicular Helper T Cells Correlates with Dyslipidemia and WBC Count in Atherosclerosis

Background: The significance of cTfh cells and their subsets in atherosclerosis is not well understood. We measured the frequency of cTfh subsets in patients with different degrees of stenosis using flow-cytometry. Methods: Participants included high (≥50%; n = 12) and low (<50%; n = 12) stenosis groups, as well as healthy controls (n = 6). Results: The frequency of CCR7loPD-1hiefficient-cTfh w...

When Teams Can ’ t Decide

T Helper Cells Profile and CD4+CD25+Foxp3+Regulatory T Cells in Polycystic Ovary Syndrome

Background: Polycystic ovary syndrome (PCOS) is considered as the most common cause of female infertility that affects 4-10% of women in the reproductive age. Previous studies have shown the role of a balanced immune response in a successful pregnancy and fertility. Objective: To investigate the T helper cells type 1 (Th1) /Th2/Th17/Treg paradigms in peripheral blood of infertile PCOS compared ...